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CAS 126-72-7

Tris(2,3-dibromopropyl) phosphate

Potential EDCCarcinogen

Tris(2,3-dibromopropyl) phosphate (TDBPP) is a brominated flame retardant once added to children’s sleepwear and other textiles. It is toxic; animal studies show it causes cancer, and health agencies consider it a likely human carcinogen, which led to most uses being halted [1][2][3].

Where It Comes From

Formerly used in fabrics, plastics, and foam; now mainly encountered in older treated items and at contaminated waste sites [1][2].

How You Are Exposed

Skin contact with old treated clothing/foam, breathing or ingesting indoor dust, workplace air/dust when handling legacy materials, or contact with soil/water near waste sites [1][2].

Why It Matters

Damages DNA and caused tumors in animals; EPA classifies it as a probable human carcinogen; IARC has evaluated it for carcinogenicity. Skin can absorb it; it may irritate skin and eyes [1][2][3].

Who Is at Risk

Workers in manufacturing, recycling, or disposal of flame‑retarded goods; people using decades‑old treated textiles; young children who mouth fabrics or ingest dust; residents near contaminated sites [1][2].

How to Lower Your Exposure

Avoid or replace vintage flame‑retardant sleepwear; reduce dust with wet cleaning and HEPA vacuuming; wash hands often; handle suspect old foam/fabrics with gloves and seal for disposal; follow workplace protections [1][2].

References

  1. [1]ATSDR. ToxFAQs for Tris(2,3-dibromopropyl) phosphate (TRIS). Agency for Toxic Substances and Disease Registry.
  2. [2]U.S. EPA. Hazard Summary—Tris(2,3-dibromopropyl) phosphate. Technology Transfer Network Air Toxics.
  3. [3]IARC. Monographs on the Evaluation of Carcinogenic Risks to Humans: Tris(2,3-dibromopropyl) phosphate. International Agency for Research on Cancer.

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