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CAS TOTAL MICROCYSTINS

TOTAL MICROCYSTINS

Microcystins are liver-damaging toxins made by certain freshwater algae (cyanobacteria). They can contaminate lakes, rivers, and drinking water during harmful algal blooms (HABs) [1][3]. They matter because they can cause acute illness and possibly cancer [1][4].

Where It Comes From

Made by cyanobacteria in warm, nutrient-rich water; blooms are fueled by runoff and heat. Toxins can persist after blooms die and enter drinking water. “Total microcystins” is the combined amount of variants, often measured as MC‑LR equivalents [1][2][3].

How You Are Exposed

Drinking contaminated water; swimming/boating in bloom-affected water; breathing spray; eating contaminated fish (especially organs) or produce irrigated with tainted water; rare dialysis exposures [1][3][5].

Why It Matters

Primarily a liver toxin—can cause nausea, vomiting, diarrhea, abdominal pain, and jaundice; severe cases can injure the liver. IARC: microcystin‑LR is possibly carcinogenic (Group 2B) [1][4]. WHO guideline: 1 μg/L (as MC‑LR); EPA 10‑day advisories: 0.3 μg/L (young children) and 1.6 μg/L (older children/adults) [2][3].

Who Is at Risk

Infants and young children, pregnant people, those with liver/kidney disease, people using untreated surface water, frequent swimmers/boaters near blooms, and pets [1][3][5].

How to Lower Your Exposure

Follow HAB/drinking water advisories; avoid water that looks like paint/pea soup or has scum; do not boil contaminated water; use safe alternate water; rinse fish fillets and discard guts; keep pets out; shower after water activities [2][3][5].

References

  1. [1]ATSDR. Cyanobacterial Toxins (Cyanotoxins): Case Studies in Environmental Medicine. https://www.atsdr.cdc.gov/csem/cyanobacterial-toxins/index.html
  2. [2]WHO. Cyanobacterial toxins: microcystins. Background document for WHO drinking-water guidelines (2020). https://apps.who.int/iris/handle/10665/338066
  3. [3]EPA. Drinking Water Health Advisories for Cyanotoxins (Microcystins, Cylindrospermopsin). https://www.epa.gov/cyanohabs/epa-drinking-water-health-advisories-cyanotoxins
  4. [4]IARC Monographs Vol. 94. Ingested Nitrate and Nitrite, and Cyanobacterial Peptide Toxins (2010). https://publications.iarc.fr/110
  5. [5]CDC. Prevent Illness from Harmful Algal Blooms. https://www.cdc.gov/harmful-algal-blooms/prevention-control.html

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