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CAS 97553-95-2

Thiocyanic acid, γ-ω-perfluoro-C4-20-alkyl esters

These are PFAS “precursor” chemicals used to make stain- and water‑repellent coatings and fluorinated surfactants [1][2]. They can transform into persistent PFAS (like PFOA) that build up in people and the environment [1][2].

Where It Comes From

Industrial production of fluorinated surfactants and coatings; present as intermediates/impurities in AFFF foams and treated textiles/paper; releases from manufacturing and product breakdown [1][2].

How You Are Exposed

Drinking contaminated water near PFAS facilities, airports, or fire training sites; indoor dust from treated carpets/upholstery; some foods and fish; workplace inhalation/skin contact [1][2].

Why It Matters

Many PFAS are linked with higher cholesterol, liver and thyroid changes, reduced vaccine response, and developmental effects; PFOA is carcinogenic to humans [1][3][4].

Who Is at Risk

PFAS workers and firefighters; communities using contaminated private wells; people eating locally caught fish from affected waters; pregnant people, infants, and children [1][2].

How to Lower Your Exposure

Use certified PFAS‑reducing water filters (NSF/ANSI 53 or 58) if needed; follow fish advisories; reduce stain‑resistant sprays/treatments; wet‑dust and use a HEPA vacuum; follow workplace protections [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. Technical Fact Sheet – Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoic Acid (PFOA). https://www.epa.gov/fedfac/technical-fact-sheet-perfluorooctane-sulfonate-pfos-and-perfluorooctanoic-acid
  3. [3]NTP. Monograph on Immunotoxicity Associated with PFOA and PFOS. 2016. https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/immune
  4. [4]IARC. Monographs Volume 135: Perfluorooctanoic acid (PFOA) and Perfluorooctanesulfonic acid (PFOS). 2023. https://publications.iarc.fr/604

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