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CAS 116-14-3

Tetrafluoroethylene (Tetrafluoroethene)

Tetrafluoroethylene (TFE) is a colorless, highly flammable gas used to make nonstick and other fluoropolymer plastics. Breathing it can harm your lungs and nervous system, and it shows cancer potential in animals [1][2].

Where It Comes From

Produced to make PTFE (Teflon) and other fluoropolymers; releases can occur during manufacturing, storage, or transport incidents [1][3].

How You Are Exposed

Mainly by breathing workplace air where TFE is made or used; the public may be exposed near facilities or during spills. You may not notice it by smell [1][3].

Why It Matters

Short-term exposure can cause dizziness, headache, throat/lung irritation, and serious lung injury at high levels. Animal studies show tumors; IARC classifies TFE as probably carcinogenic to humans (Group 2A) [1][2][3].

Who Is at Risk

Fluoropolymer production and maintenance workers, transport workers, contractors at these sites, nearby communities during incidents, and emergency responders [1][3].

How to Lower Your Exposure

At work, use closed systems, ventilation, leak detection, and required PPE/respirators. In communities, follow local air alerts and incident guidance (shelter-in-place/evacuate) and report suspected releases [1][3].

References

  1. [1]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Tetrafluoroethylene (CAS 116-14-3).
  2. [2]IARC. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Tetrafluoroethylene (Group 2A).
  3. [3]U.S. EPA. Tetrafluoroethylene: IRIS/Hazard Summary and Air Toxics information.

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