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CAS 335-95-5

Sodium perfluorooctanoate

Sodium perfluorooctanoate (NaPFOA) is a PFAS surfactant used to make nonstick and stain‑resistant products; in water and the body it dissociates to PFOA, a persistent “forever chemical.” PFOA is linked to cancer and other health harms [1][2][3].

Where It Comes From

Fluoropolymer manufacturing, AFFF firefighting foams, treated textiles/carpets, and food‑contact coatings; releases from factories, landfills, and spills [1][4].

How You Are Exposed

Drinking contaminated tap or well water, eating contaminated fish/food, indoor dust, and some workplaces (fluorochemical production, firefighting) [1][4].

Why It Matters

Builds up in people for years; associated with higher cholesterol, reduced vaccine antibody response, liver and thyroid effects, pregnancy‑induced hypertension, and kidney and testicular cancers [1][2][3]. EPA’s drinking‑water MCL for PFOA is 4 ppt [4].

Who Is at Risk

Pregnant people, fetuses/infants, communities near affected facilities or bases, private‑well users, and exposed workers [1][4].

How to Lower Your Exposure

Test well water; use certified filters (NSF/ANSI 53 carbon or 58 reverse osmosis) for PFOA; follow local water and fish advisories; choose fewer stain‑resistant products; wet‑dust/HEPA‑vacuum; and follow workplace controls [1][4][5].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (2021). https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]IARC. Carcinogenicity of perfluorooctanoic acid (PFOA) (2023). https://www.iarc.who.int/wp-content/uploads/2023/12/pr264_E.pdf
  3. [3]NTP. Monograph on Immunotoxicity of PFOA and PFOS (2016). https://ntp.niehs.nih.gov/ntp/ohat/pfoa_pfos/pfoa_pfosmonograph_508.pdf
  4. [4]U.S. EPA. PFAS National Primary Drinking Water Regulation (2024). https://www.epa.gov/sdwa/and-polyfluoroalkyl-substances-pfas/epas-pfas-national-primary-drinking-water-regulation
  5. [5]U.S. EPA. Steps to reduce your risk from PFAS (filters, advisories) (2023). https://www.epa.gov/pfas/meaningful-and-achievable-steps-you-can-take-reduce-your-risk

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