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CAS 7632-00-0

Sodium nitrite

Sodium nitrite is a preservative and industrial chemical used to cure meats and prevent corrosion. At high levels it reduces the blood’s ability to carry oxygen (methemoglobinemia) and can form nitrosamines linked to cancer risk [1][2].

Where It Comes From

Cured meats; corrosion inhibitors and manufacturing (dyes, chemicals); and can form in drinking water when nitrate is converted by bacteria [1][4].

How You Are Exposed

Eating processed meats; drinking or making infant formula with contaminated well water; workplace inhalation/skin contact with powders or solutions; accidental ingestion from mislabeled containers [1][3][4].

Why It Matters

Symptoms include headache, dizziness, shortness of breath, bluish skin; severe poisoning can be fatal. Ingested nitrite under conditions that create nitrosamines is probably carcinogenic (IARC Group 2A) [1][2].

Who Is at Risk

Infants under 6 months; pregnant people; those with anemia, heart/lung disease, or enzyme deficiencies; and workers in meat curing or chemical production [1][3].

How to Lower Your Exposure

Limit processed meats; test private wells for nitrate/nitrite and use certified treatment or alternative water if elevated; store and label chemicals securely; follow workplace controls, PPE, and hygiene [1][3][4].

References

  1. [1]ATSDR. Nitrate and Nitrite ToxFAQs. https://www.atsdr.cdc.gov/toxfaqs/tfacts204.pdf
  2. [2]IARC. Monographs Vol. 94: Ingested Nitrate and Nitrite. https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono94.pdf
  3. [3]CDC/NIOSH. Pocket Guide: Sodium nitrite. https://www.cdc.gov/niosh/npg/npgd0576.html
  4. [4]EPA. National Primary Drinking Water Regulations (Nitrite). https://www.epa.gov/ground-water-and-drinking-water/national-primary-drinking-water-regulations

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