Where It Comes From
Cured meats; corrosion inhibitors and manufacturing (dyes, chemicals); and can form in drinking water when nitrate is converted by bacteria [1][4].
How You Are Exposed
Eating processed meats; drinking or making infant formula with contaminated well water; workplace inhalation/skin contact with powders or solutions; accidental ingestion from mislabeled containers [1][3][4].
Why It Matters
Symptoms include headache, dizziness, shortness of breath, bluish skin; severe poisoning can be fatal. Ingested nitrite under conditions that create nitrosamines is probably carcinogenic (IARC Group 2A) [1][2].
Who Is at Risk
Infants under 6 months; pregnant people; those with anemia, heart/lung disease, or enzyme deficiencies; and workers in meat curing or chemical production [1][3].
How to Lower Your Exposure
Limit processed meats; test private wells for nitrate/nitrite and use certified treatment or alternative water if elevated; store and label chemicals securely; follow workplace controls, PPE, and hygiene [1][3][4].
References
- [1]ATSDR. Nitrate and Nitrite ToxFAQs. https://www.atsdr.cdc.gov/toxfaqs/tfacts204.pdf
- [2]IARC. Monographs Vol. 94: Ingested Nitrate and Nitrite. https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono94.pdf
- [3]CDC/NIOSH. Pocket Guide: Sodium nitrite. https://www.cdc.gov/niosh/npg/npgd0576.html
- [4]EPA. National Primary Drinking Water Regulations (Nitrite). https://www.epa.gov/ground-water-and-drinking-water/national-primary-drinking-water-regulations