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CAS 78560-44-8

Silane, trichloro(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-

This fluorinated silane is used to make water- and oil-repellent coatings on glass, electronics, and other surfaces. It is corrosive, reacts with moisture to release hydrochloric acid, and its PFAS-like tail raises persistence and health concerns [3][1][2].

Where It Comes From

Manufactured for thin, nonstick surface treatments (electronics/MEMS, optics, molds, labware) and applied by vapor or spray processes [3].

How You Are Exposed

Mainly at work during handling, mixing, deposition, cleanup, or spills; small amounts may off-gas from freshly treated items [3][2].

Why It Matters

Moisture contact can release HCl that burns eyes/skin and irritates lungs; PFAS can persist, build up, and some have been linked to immune, cholesterol, and cancer outcomes [3][1][4][2].

Who Is at Risk

Workers in coating/electronics plants; contractors applying coatings; people near production sites; pregnant people, infants, and those with asthma or poor ventilation [1][2][3].

How to Lower Your Exposure

At work: closed systems, local exhaust, acid-resistant gloves/goggles, HCl monitoring, spill kits, training [3][5]. At home: choose PFAS-free options, avoid DIY sprays, ventilate, keep coated items intact, follow disposal guidance [2][1].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021.
  2. [2]U.S. EPA. Our Current Understanding of the Human Health and Environmental Risks of PFAS. 2024.
  3. [3]CDC/NIOSH. Chlorosilanes: Workplace Safety and Health Topic. cdc.gov/niosh/topics/chlorosilanes
  4. [4]IARC. PFOA classified as carcinogenic to humans (Press Release 264). 2023.
  5. [5]ATSDR. ToxFAQs: Hydrogen Chloride (HCl). 2016.

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