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CAS 31218-83-4

Propetamphos

Propetamphos is an organophosphate insecticide used to control household pests like cockroaches and ants. It harms the nervous system by inhibiting cholinesterase; some U.S. uses have been canceled or restricted due to health risks [1][3].

Where It Comes From

Professional pest-control products and treatments in buildings; use and approvals vary by country [1].

How You Are Exposed

Breathing spray mist, skin contact during application, touching treated surfaces or dust and then hand-to-mouth, and occupational handling; food or water are less common routes for this mainly indoor-use pesticide [1][3].

Why It Matters

Can cause headache, dizziness, nausea, sweating, and pinpoint pupils; high exposures may lead to breathing trouble, seizures, or even death. Repeated exposure can depress blood cholinesterase. WHO classifies propetamphos as moderately hazardous (Class II) [2][3].

Who Is at Risk

Pest-control workers; people present during indoor treatments; young children who crawl and mouth surfaces; and individuals who are pregnant or have asthma or reduced detox enzymes may be more sensitive [2][3].

How to Lower Your Exposure

Prefer integrated pest management (seal entry points, clean up food/water sources). If treatment uses propetamphos, leave during application, ventilate well, and keep children/pets away until dry. Always follow the label; wear gloves; wash hands and work clothes separately. Workers may need routine cholinesterase testing [1][3].

References

  1. [1]U.S. EPA. Propetamphos (pesticide chemical search/registration status and risk information).
  2. [2]WHO. The WHO Recommended Classification of Pesticides by Hazard (Propetamphos listed as Class II).
  3. [3]ATSDR. Organophosphate Insecticides—ToxFAQs/Medical Management Guidelines (cholinesterase inhibition, exposure routes, health effects).

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