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CAS 1918-16-7

Propachlor

PesticidesCarcinogen

Propachlor is a weed‑killer (herbicide) used on crops like corn and sorghum. It can move from fields into soil and water; high exposures have harmed the liver and kidneys in animal studies [1][2].

Where It Comes From

Agricultural use; runoff can carry it to streams, and it can seep into groundwater and private wells [1][3].

How You Are Exposed

Drinking contaminated well water; contact with treated soil/equipment; breathing spray drift; occupational mixing/applying. Food is usually a smaller source where use is limited [1][2].

Why It Matters

Short-term exposure can irritate skin and eyes; repeated exposure has caused liver and kidney changes and tumors in animals. Evidence for cancer in humans is insufficient [1][2].

Who Is at Risk

Farmworkers and applicators; people living near treated fields; private‑well users near agriculture; pregnant people, infants, and children (more sensitive to toxic effects) [1][3].

How to Lower Your Exposure

Follow posted re‑entry times and avoid drift; wash produce; if you use a private well near fields, test for herbicides and consider NSF/ANSI Standard 53 (activated carbon) or 58 (reverse osmosis) certified filters; follow workplace protections (gloves, eyewear, respirators as directed) [3][4].

References

  1. [1]U.S. EPA, Integrated Risk Information System (IRIS): Propachlor (CASRN 1918-16-7).
  2. [2]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Propachlor.
  3. [3]U.S. EPA, 2023 Edition of the Drinking Water Standards and Health Advisories.
  4. [4]U.S. EPA, Protect Your Tap: A Guide to Water Filters and Testing.

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