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CAS 122-99-6

Phenyl Cellosolve

Phenyl Cellosolve (2‑phenoxyethanol) is a solvent and preservative found in some cosmetics, cleaners, inks/paints, and a few vaccines [1][2][3]. It can irritate skin and eyes and, at high levels, affect the nervous system [1].

Where It Comes From

Industrially made; used as a solvent in inks, paints, and detergents, and as a preservative in personal care products and some vaccines [1][2][3].

How You Are Exposed

Mostly through skin contact or breathing vapors when using products; workplace exposure in printing, painting, or cleaning; small amounts via vaccination [1][2].

Why It Matters

Irritates eyes/skin and is absorbed through skin; high doses can cause headache, dizziness, nausea/vomiting; severe effects reported in infants from topical products. Not listed as a carcinogen by NTP; cancer data are limited [1][4][5].

Who Is at Risk

Workers handling solvents; infants/young children; people with skin conditions or asthma; pregnant workers handling large quantities should minimize exposure as a precaution [1][4].

How to Lower Your Exposure

Check labels for “phenoxyethanol”; use products in well‑ventilated areas; wear gloves; avoid use on infant skin unless directed; follow workplace controls; store products away from children [1][2][4].

References

  1. [1]WHO/ILO/NIOSH. International Chemical Safety Card (ICSC) 0832: 2‑Phenoxyethanol. https://www.ilo.org/legacy/english/protection/safework/cis/cisdig.htm
  2. [2]CDC. Common Ingredients in U.S. Licensed Vaccines. https://www.cdc.gov/vaccines/vac-gen/additives.htm
  3. [3]EPA/NOAA. CAMEO Chemicals: 2‑Phenoxyethanol. https://cameochemicals.noaa.gov/chemical/19774
  4. [4]U.S. FDA. FDA warns moms about the use of Mommy’s Bliss Nipple Cream. https://www.fda.gov/news-events/press-announcements/fda-warns-moms-about-use-mommys-bliss-nipple-cream
  5. [5]NTP. Report on Carcinogens—Substances Listed. https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/roc

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