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CAS 4149-60-4

PFNA

Perfluorononanoic acid (PFNA) is a man‑made PFAS “forever chemical” used in making nonstick and water‑/oil‑repellent products. It persists in the environment, can contaminate drinking water, and builds up in people’s bodies [1][2].

Where It Comes From

Fluorochemical manufacturing and processing, some firefighting foams, and treated textiles/packaging; it does not break down easily [1][2].

How You Are Exposed

Drinking contaminated water, eating contaminated fish or food, breathing or ingesting dust at home, and certain workplaces (chemical plants, plating, textiles, firefighting) [1][3].

Why It Matters

PFAS like PFNA have been linked to higher cholesterol, liver effects, reduced vaccine response/other immune changes, and developmental effects; animal studies show liver and developmental toxicity [1][2][4].

Who Is at Risk

People with PFAS‑contaminated water, workers handling PFAS or AFFF, pregnant people, infants and children, and communities near sites using or making PFAS [1][2].

How to Lower Your Exposure

Check your water report; if PFAS are elevated, use certified PFAS‑reducing filters (activated carbon or reverse osmosis), follow local fish advisories, minimize products marketed as stain‑/water‑resistant that may contain PFAS, and reduce indoor dust with wet cleaning/HEPA vacuuming; discuss infant feeding and water choices with a clinician—don’t stop breastfeeding solely due to PFAS [1][2][3].

References

  1. [1]ATSDR. Per- and Polyfluoroalkyl Substances (PFAS) and Your Health. ToxFAQs/Agency resources, 2021–2023.
  2. [2]U.S. EPA. PFAS National Primary Drinking Water Regulation (2024) and Learn About PFAS: Health and Exposure.
  3. [3]CDC. National Biomonitoring Program: PFAS Factsheet; National Report on Human Exposure to Environmental Chemicals.
  4. [4]NTP. Immunotoxicity associated with exposure to PFOA and PFOS (Monograph), 2016.

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