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CAS 21615-47-4

PFHXA

Selected Per- and poly-fluoroalkyl substances (PFAS)PFAS

PFHxA (perfluorohexanoic acid) is a short-chain PFAS used in water‑ and stain‑resistant products and can form as other PFAS break down. It persists in the environment and can reach drinking water supplies [1][2].

Where It Comes From

Made for coatings on textiles, carpets, paper/packaging, and as a breakdown product of fluorotelomer chemicals; also linked to firefighting foams and industrial discharges [1][2].

How You Are Exposed

Primarily through drinking water; also via food, indoor dust, and some treated consumer products; workers may be exposed on the job [1][2].

Why It Matters

PFHxA is very persistent and mobile in water. While it bioaccumulates less than some older PFAS, studies indicate potential effects on the liver, thyroid hormones, kidneys, and development, mainly from animal data; human data are limited [1][2].

Who Is at Risk

People using contaminated private wells or community systems near PFAS facilities or airports; pregnant people, fetuses, and infants; firefighters and workers handling PFAS-containing materials [1][2].

How to Lower Your Exposure

Check local water quality. Use home water treatment certified for PFAS (activated carbon or reverse osmosis). Avoid “stain‑resistant” treatments and grease‑resistant food packaging when possible, reduce indoor dust, and follow workplace safety guidance [2][3].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. Our Current Understanding of the Human Health and Environmental Risks of PFAS. https://www.epa.gov/pfas/our-current-understanding-human-health-and-environmental-risks-pfas
  3. [3]ATSDR/CDC. PFAS and Your Health: Information for Families and Communities. https://www.atsdr.cdc.gov/pfas/health-effects/index.html

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