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CAS 376-06-7

Perfluorotetradecanoic acid

Perfluorotetradecanoic acid (PFTDA) is a long‑chain PFAS (“forever chemical”) used in some industrial processes and formed when other PFAS break down. It persists in the environment and can build up in people [1][2].

Where It Comes From

Fluoropolymer manufacturing and water/oil‑repellent coatings; breakdown of fluorotelomer PFAS into long‑chain perfluorocarboxylic acids like PFTDA [1][2].

How You Are Exposed

Drinking water near PFAS‑using factories or firefighting sites; eating contaminated fish/foods; indoor dust; treated textiles/packaging; workplace exposure [1][2].

Why It Matters

Data on PFTDA are limited, but long‑chain PFAS have been linked to higher cholesterol, liver and immune effects, and developmental impacts; PFOA (a related PFAS) is carcinogenic to humans [1][3][4].

Who Is at Risk

Communities with PFAS‑contaminated water, PFAS‑industry workers, pregnant people, infants/children, and frequent consumers of local fish/wildlife [1][2].

How to Lower Your Exposure

Check local water results; use certified activated carbon or reverse osmosis filters for PFAS; follow fish advisories; limit stain/water‑resistant products; wet‑dust/HEPA vacuum; follow workplace protections [2][5].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021.
  2. [2]U.S. EPA. Basic Information on PFAS (exposure, persistence, reducing risk). 2023–2024.
  3. [3]NTP. Immunotoxicity of PFOA and PFOS. 2016.
  4. [4]IARC. PFOA carcinogenic to humans; PFOS possibly carcinogenic. Press Release No. 264, 2023.
  5. [5]CDC/ATSDR. PFAS and Your Health – Reducing Exposure (water filters, fish advisories).

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