← All chemicals

CAS 355-46-4

Perfluorohexanesulfonic acid

Selected Per- and poly-fluoroalkyl substances (PFAS)Potential EDCPFAS

PFHxS is a man-made “forever chemical” used for stain, water, and grease resistance and in firefighting foams. It persists and can build up in people; studies link it to immune effects, higher cholesterol, and developmental and liver changes [1][2].

Where It Comes From

AFFF foams; stain- and water-repellent treatments on textiles, carpets, and paper; industrial discharges and landfills; and breakdown of related PFAS [1][2].

How You Are Exposed

Drinking contaminated tap or well water; eating contaminated fish or game; indoor dust; and workplace contact in firefighting, airports, or PFAS-using industries [1][2].

Why It Matters

Builds up in the body for years; most people have some in their blood. Exposure has been linked to reduced vaccine response, higher cholesterol, liver and thyroid changes, and effects during pregnancy and childhood [1][3].

Who Is at Risk

People on private wells near airports, military bases, or PFAS facilities; pregnant people, infants and children; and workers handling AFFF or PFAS [1][2].

How to Lower Your Exposure

Test your water; use certified activated carbon or reverse-osmosis filters for PFAS; follow fish advisories; reduce dust (wet clean/HEPA vacuum); and limit stain- or water-resistant products [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]EPA. Our Current Understanding of the Human Health and Environmental Risks of PFAS. https://www.epa.gov/pfas/our-current-understanding-human-health-and-environmental-risks-pfas
  3. [3]CDC. National Biomonitoring Program: PFAS Factsheet. https://www.cdc.gov/biomonitoring/PFAS_FactSheet.html

Track your exposure to Perfluorohexanesulfonic acid

Pollution Profile maps your lifetime exposure history to EPA-tracked chemicals.

Get early access

We use cookies and analytics to understand how people use Pollution Profile and improve the experience. We never sell your data. Learn more.