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CAS 45187-15-3

Perfluorobutanesulfonate

Perfluorobutanesulfonate (PFBS) is a short‑chain PFAS used as a replacement for PFOS in stain‑resistant products, firefighting foams, and industrial processes. It persists in the environment and can contaminate drinking water; studies suggest potential thyroid and liver effects [1][2].

Where It Comes From

Made/used in repellents, AFFF, metal plating, paper, and textiles; now found in water, soil, and sludge due to its persistence [1][2].

How You Are Exposed

Drinking contaminated tap or well water; eating contaminated fish/food; indoor dust from treated carpets/fabrics; workplace air or skin contact [1].

Why It Matters

Less bioaccumulative than some PFAS but may affect thyroid hormones, liver, kidneys, and development at sufficient doses. EPA’s 2024 drinking‑water rule includes PFBS via a PFAS Hazard Index [1][2].

Who Is at Risk

People near PFAS manufacturing/plating, landfills, or AFFF sites; private‑well users; firefighters and certain industrial workers; pregnant people, fetuses, and infants using formula mixed with contaminated water [1][2].

How to Lower Your Exposure

Check local water results; use NSF/ANSI 53 (carbon) or 58 (reverse osmosis) filters certified for PFAS; follow fish advisories; limit stain‑resistant/water‑repellent products; follow workplace protections [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. PFAS National Primary Drinking Water Regulation (Final Rule). 2024. https://www.epa.gov/sdwa/epas-pfas-national-primary-drinking-water-regulation

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