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CAS 57-33-0

Pentobarbital sodium

Pentobarbital sodium is a powerful barbiturate sedative used for anesthesia, seizure control, and veterinary euthanasia [1][2]. It matters because overdoses can slow breathing and cause coma or death, and it has occasionally been found in pet food or animal remains, posing risks to people and animals [2][3].

Where It Comes From

Prescription medicine and hospital anesthesia; veterinary euthanasia solutions; waste from clinics and animal carcass disposal [1][2][3].

How You Are Exposed

Taking it as a medicine; misuse; accidental swallowing by children or pets; handling euthanasia solutions in vet settings; pets eating contaminated food or scavenging euthanized animals [2][3].

Why It Matters

Causes drowsiness, poor coordination, slowed breathing, low blood pressure; high doses can be fatal; mixing with alcohol, opioids, or other sedatives greatly increases risk; repeated use can lead to dependence and withdrawal [2][4].

Who Is at Risk

People using other depressants or with breathing or liver problems; pregnant people, children, and older adults; veterinary staff; pets and wildlife that access euthanized animals [2][3].

How to Lower Your Exposure

Use only as prescribed; avoid alcohol/other sedatives unless directed; store locked, out of reach; dispose via take-back or FDA-recommended methods; follow workplace safety and local rules for handling and disposing of euthanized animals [2][3][5].

References

  1. [1]NIH/NLM PubChem. Pentobarbital sodium. https://pubchem.ncbi.nlm.nih.gov/compound/Pentobarbital-sodium
  2. [2]FDA DailyMed. Pentobarbital Sodium Injection, USP – Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/
  3. [3]FDA CVM. FDA investigation: pentobarbital in dog food. https://www.fda.gov/animal-veterinary/outbreaks-and-advisories/fda-investigation-pentobarbital-dog-food
  4. [4]NIH/NLM MedlinePlus. Barbiturate intoxication and overdose. https://medlineplus.gov/ency/article/000951.htm
  5. [5]FDA. Disposal of Unused Medicines: What You Should Know. https://www.fda.gov/drugs/safe-disposal-medicines/disposal-unused-medicines-what-you-should-know

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