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CAS 16517-11-6

Octadecanoic acid, pentatriacontafluoro-

Octadecanoic acid, pentatriacontafluoro- (CAS 16517-11-6) is a long‑chain PFAS (“forever chemical”). It’s used in industrial water- and oil‑repellent applications and is extremely persistent, meaning it can remain in the environment and bodies for years [1][2].

Where It Comes From

Production and use of fluorinated coatings and fluoropolymers; releases from manufacturing sites, treated products, and waste streams; PFAS-contaminated sites (including where firefighting foams were used) [1][2].

How You Are Exposed

Drinking contaminated water, eating contaminated fish/food, breathing or ingesting indoor dust from treated carpets/upholstery, and at workplaces that handle PFAS [1][2].

Why It Matters

Data on this exact PFAS are limited, but long‑chain PFAS persist and can build up in people. Related PFAS are linked to higher cholesterol, liver and thyroid changes, lower vaccine response, developmental effects, and, for PFOA, cancer in humans [1][3][4].

Who Is at Risk

Workers in fluorochemical industries; people using contaminated private wells or living near PFAS sites; pregnant people, infants (placental and breast‑milk transfer); frequent consumers of locally caught fish where PFAS advisories exist [1][2].

How to Lower Your Exposure

Check local water reports; use certified filters (activated carbon or reverse osmosis) for PFAS; follow fish advisories; minimize stain/grease‑resistant treatments; reduce indoor dust; follow workplace safety practices [1][2][5].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (2021).
  2. [2]U.S. EPA. PFAS Explained / Human Health and Environmental Risks of PFAS (accessed 2024–2025).
  3. [3]NTP. Monograph on Immunotoxicity of PFOA and PFOS (2016).
  4. [4]IARC. Monographs Vol. 131: Some Per- and Polyfluoroalkyl Substances (2023) – PFOA Group 1.
  5. [5]WHO. PFOS and PFOA in Drinking-water: Background document (2022) – treatment with GAC/RO.

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