← All chemicals

CAS NPYR

NPYR

N‑Nitrosopyrrolidine (NPYR) is a nitrosamine—a toxic chemical that can form in foods, tobacco smoke, certain industries, and sometimes drinking water. It causes cancer in animals; IARC classifies it as possibly carcinogenic to humans, and NTP lists it as reasonably anticipated to be a human carcinogen [2][3].

Where It Comes From

Forms when amines and nitrite react; found in cured/smoked meats, beer, tobacco smoke, rubber/leather manufacturing; can form during chloraminated water treatment [1][2][4].

How You Are Exposed

Eating processed meats or beer; breathing tobacco smoke or some workplace air; drinking chloraminated water [1][2][4].

Why It Matters

Long‑term exposure raises cancer risk and can harm the liver [1][2][3].

Who Is at Risk

Smokers and people around smoke; workers in rubber/leather/metal‑working; heavy consumers of cured meats; people served by chloraminated systems where nitrosamines occur [1][2][3][4].

How to Lower Your Exposure

Don’t smoke; limit cured/smoked meats and high‑heat frying; check your water report; consider home treatment (activated carbon, reverse osmosis, or UV) and workplace controls/PPE [1][4].

References

  1. [1]WHO. N‑Nitrosamines in Drinking‑water: Background document for development of WHO Guidelines for Drinking‑water Quality. 2011.
  2. [2]IARC. Some N‑Nitroso Compounds. IARC Monographs Vol. 17 and Suppl. 7; classification of N‑nitrosopyrrolidine (Group 2B).
  3. [3]NTP. Report on Carcinogens, 15th Ed. N‑Nitrosopyrrolidine. 2021.
  4. [4]U.S. EPA. Technical Fact Sheet: NDMA and Other Nitrosamines; occurrence, formation during chloramination, and treatment.

Track your exposure to NPYR

Pollution Profile maps your lifetime exposure history to EPA-tracked chemicals.

Get early access

We use cookies and analytics to understand how people use Pollution Profile and improve the experience. We never sell your data. Learn more.