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CAS N535

Nonylphenol Ethoxylates

Nonylphenol ethoxylates (NPEs) are detergent-like chemicals used in industrial cleaners, textiles, and some pesticides. They break down into nonylphenol, which can disrupt hormones and harm aquatic life, raising health and environmental concerns [1][2].

Where It Comes From

Industrial/institutional detergents, textile and paper processing, paints and pesticide formulations; released to water with laundry and factory wastewater [1][2].

How You Are Exposed

Skin contact or breathing mists when using cleaners, handling treated textiles, or at work; drinking water or eating fish/shellfish from contaminated waters [1][2].

Why It Matters

NPEs degrade to nonylphenol, which is persistent and bioaccumulative, shows estrogen-like activity, and is highly toxic to aquatic organisms; animal studies report reproductive and developmental effects [1][2].

Who Is at Risk

Workers in industrial laundry, cleaning, textiles, and pulp/paper; people who frequently eat locally caught fish from polluted areas; communities near wastewater discharges [1][2].

How to Lower Your Exposure

Choose NPE-free or EPA Safer Choice–certified products; read labels for “nonylphenol ethoxylate” or “NPE”; follow directions and avoid overuse; at work, use ventilation, gloves, and other PPE; dispose of products and wash water as directed to limit releases [1][3].

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