← All chemicals

CAS N503

Nicotine and salts

Nicotine and its salts are highly addictive chemicals found in tobacco and many vaping liquids. They stimulate the nervous system and can be toxic at high doses, especially for children [1][2].

Where It Comes From

Tobacco plants; cigarettes, cigars, and smokeless tobacco; e‑cigarette/vape liquids (including nicotine salts); some quit‑smoking medicines contain nicotine [1][2].

How You Are Exposed

Inhaling smoke or vapor; swallowing e‑liquids; skin contact from spills or handling tobacco; secondhand smoke or aerosol [1][2].

Why It Matters

Causes addiction; raises heart rate and blood pressure; can trigger nausea and vomiting; very high doses can cause seizures and death; harmful during pregnancy and to teen brain development [1][2][3].

Who Is at Risk

Pregnant people and fetuses; infants and children; teens; people with heart disease; workers handling tobacco leaves or nicotine liquids [1][2][3][4].

How to Lower Your Exposure

Don’t smoke or vape; avoid secondhand smoke/aerosol; store e‑liquids locked and in child‑resistant containers; clean spills with gloves and wash skin; use approved quit‑smoking aids as directed; seek medical care or poison help after significant exposure [1][2][3].

References

  1. [1]ATSDR. ToxFAQs for Nicotine and Related Compounds. https://www.atsdr.cdc.gov/toxfaqs/tfacts121.pdf
  2. [2]CDC. Quick Facts on the Risks of E‑cigarettes for Kids, Teens, and Young Adults. https://www.cdc.gov/tobacco/basic_information/e-cigarettes/Quick-Facts-on-the-Risks-of-E-cigarettes-for-Kids-Teens-and-Young-Adults.html
  3. [3]WHO. Q&A on e‑cigarettes. https://www.who.int/news-room/questions-and-answers/item/e-cigarettes-and-similar-devices
  4. [4]CDC/NIOSH. Green Tobacco Sickness. https://www.cdc.gov/niosh/topics/greentobaccosickness/

Track your exposure to Nicotine and salts

Pollution Profile maps your lifetime exposure history to EPA-tracked chemicals.

Get early access

We use cookies and analytics to understand how people use Pollution Profile and improve the experience. We never sell your data. Learn more.