Where It Comes From
Nickel smelting and refining; production of nickel powders and catalysts; byproduct of processing sulfide ores; emissions from refineries and some high‑temperature metalwork [1][2].
How You Are Exposed
Mainly at work by inhaling dust or fumes; less commonly by skin contact; people near facilities may have low‑level air or dust exposure; take‑home contamination on work clothes [1][2].
Why It Matters
Classified carcinogenic to humans; raises risk of lung and nasal/sinus cancer; can cause asthma‑like symptoms, chronic bronchitis, nasal irritation, and allergic skin rash in sensitized people [2][3][1].
Who Is at Risk
Workers in nickel smelting/refining, powder/catalyst manufacturing, electroplating, and other processing of nickel sulfide ores; smokers with workplace exposure; people with asthma or nickel allergy [1][2][4].
How to Lower Your Exposure
Use engineering controls and local exhaust; follow exposure limits and wear appropriate respirators and protective clothing; wash/shower and change before going home; employers should monitor air and provide training; nearby residents can reduce indoor dust by wet‑wiping, keeping outdoor dust out, and checking facility notices [1][4][5].
References
- [1]ATSDR. Toxicological Profile for Nickel. Agency for Toxic Substances and Disease Registry, 2022.
- [2]IARC. Nickel and Nickel Compounds. IARC Monographs, Volume 100C, 2012.
- [3]NTP. Report on Carcinogens, 15th Edition: Nickel Compounds. National Toxicology Program, 2021.
- [4]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Nickel subsulfide (Ni3S2).
- [5]EPA IRIS. Nickel refinery dust and nickel subsulfide (CASRN 12035-72-2): Carcinogenicity assessment and unit risk. Environmental Protection Agency.