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CAS 151772-58-6

NFDHA

NFDHA is a fluorinated amide derived from perfluorodecanoic acid (PFDA), used historically in surface treatments and as a processing aid. Like other long-chain PFAS, it is highly persistent and can transform into PFDA in the environment or the body. [1][2]

Where It Comes From

Production and use in water-, stain-, and grease-resistant coatings; degradation of PFDA precursors. [1][2]

How You Are Exposed

Drinking water impacted by PFAS sources; diet (fish, game, packaged foods); and indoor dust from treated consumer products. [2][3]

Why It Matters

Acts as a PFDA precursor; animal studies on PFDA show liver enlargement, developmental and immune effects, and cholesterol changes; specific toxicity data for NFDHA are limited. [1][3]

Who Is at Risk

Communities near fluorochemical production sites, people relying on contaminated water or seafood, and infants/children via maternal transfer. [2][3]

How to Lower Your Exposure

Follow local PFAS water advisories; use NSF/ANSI 53 or 58 certified filters to reduce PFAS; limit consumption of contaminated fish/game; reduce use of stain-resistant consumer products. [2][4]

References

  1. [1]OECD. Reconciling Terminology of the Universe of Per- and Polyfluoroalkyl Substances (PFASs), 2021.
  2. [2]U.S. EPA. PFAS Explained. U.S. Environmental Protection Agency, 2024.
  3. [3]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). Agency for Toxic Substances and Disease Registry, 2021.
  4. [4]CDC/ATSDR. PFAS and Your Health: If PFAS are in your drinking water. Centers for Disease Control and Prevention/ATSDR, 2022.

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