Where It Comes From
Forms when amines react with nitrosating agents; found in rubber/chemical manufacturing, tobacco smoke, and can form at low levels during chloraminated drinking water and wastewater treatment [2][3].
How You Are Exposed
Drinking water in some systems, tobacco smoke, certain consumer products made from rubber, and workplace air in relevant industries [2][3].
Why It Matters
Long-term exposure increases cancer risk (especially liver; tumors seen in animals) and may harm the liver [1][3].
Who Is at Risk
Workers in rubber/chemical or water treatment facilities; people who smoke or breathe secondhand smoke; communities using chloraminated water; infants consuming formula mixed with affected tap water (higher dose per body weight) [2][3].
How to Lower Your Exposure
Avoid smoking and secondhand smoke; check your water utility’s reports for nitrosamines; consider a certified reverse osmosis device if nitrosamines are present; follow workplace controls and PPE; limit use of products that may release nitrosamines and ventilate well [2][3].
References
- [1]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Some N-Nitroso Compounds, Vol. 17. International Agency for Research on Cancer.
- [2]U.S. EPA. Technical Fact Sheet – N-Nitrosamines (drinking water/wastewater formation, occurrence, treatment).
- [3]WHO/IPCS. Environmental Health Criteria 229: Selected Nitrosamines. World Health Organization.