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CAS 872-50-4

N-Methyl-2-pyrrolidone

Potential EDCDevelopmental_ToxicityTeratogen

N-Methyl-2-pyrrolidone (NMP) is a powerful solvent used in paint removers, electronics, and plastics. It readily enters the body (especially through skin) and can harm fetal development; EPA has found unreasonable risk for many uses [1][2][3].

Where It Comes From

Present in some paint/adhesive removers, coatings, cleaners, and in electronics, battery, and petrochemical manufacturing [1].

How You Are Exposed

Breathing vapors during use, skin contact from splashes or soaked gloves, and working with NMP in poorly ventilated areas [1][3].

Why It Matters

Causes eye/skin irritation; higher or repeated exposure can harm the developing fetus; EPA found unreasonable risk for workers and consumers [1][2].

Who Is at Risk

Workers handling paint strippers, coatings, cleaners, or electronics/battery manufacturing; DIY users using paint removers; people who are pregnant or planning pregnancy [1][2].

How to Lower Your Exposure

Choose NMP‑free products; check labels/SDS; use outdoors or increase ventilation; avoid skin contact and wear chemical‑resistant gloves and eye protection; follow workplace controls and keep products away from children [1][3].

References

  1. [1]U.S. EPA. Risk Evaluation for N‑Methylpyrrolidone (NMP) under TSCA. 2020 (updates 2022).
  2. [2]National Toxicology Program (NTP). NTP‑CERHR Monograph on the Potential Human Reproductive and Developmental Effects of 1‑Methyl‑2‑pyrrolidone (NMP). 2003.
  3. [3]CDC/NIOSH. Skin Notation Profiles: N‑Methyl‑2‑pyrrolidone (NMP). 2011.

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