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CAS 51218-45-2

METOLACHLOR

Organic Chemicals, except for PFASPesticidesCarcinogen

Metolachlor is a pre-emergent weed killer used widely on crops like corn and soybeans. It can move into soil and water, so people may be exposed through drinking water, food, or work with pesticides [1][3].

Where It Comes From

Applied to corn, soybeans, sorghum, peanuts, and other crops; rain and irrigation can carry it into streams and groundwater [1][3].

How You Are Exposed

Drinking water (especially private wells in farming areas), residues on food, and skin or breathing it during mixing/spraying at work [1][3].

Why It Matters

Short-term exposure can irritate eyes/skin; higher doses harmed liver and kidneys and affected development in animal studies. Evidence for cancer in humans is inadequate (IARC Group 3) [1][2][3].

Who Is at Risk

Pesticide applicators and farmworkers; residents near treated fields; people using private wells; infants, children, and pregnant people [1][3].

How to Lower Your Exposure

Check your water quality report; test private wells if you live near fields; consider NSF-certified activated carbon or reverse osmosis filters; wash produce; and follow label PPE and re-entry times [3][4].

References

  1. [1]U.S. EPA. Reregistration Eligibility Decision (RED) for Metolachlor. EPA 738-R-95-006 (1995).
  2. [2]IARC Monographs, Volume 73: Metolachlor. International Agency for Research on Cancer (1999).
  3. [3]U.S. EPA. Metolachlor/S-metolachlor: Human Health Draft Risk Assessment for Registration Review (2018).
  4. [4]U.S. EPA. Drinking Water Treatability Database: Metolachlor (accessed 2025).

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