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CAS 93-15-2

Methyleugenol

Methyleugenol is a fragrance and flavor chemical that occurs naturally in some herbs and spices and is also made for use in foods, perfumes, and other scented products. It matters because long-term, high exposures caused liver tumors in animals; it is classified as a possible/anticipated carcinogen [1][2].

Where It Comes From

Natural in essential oils of basil, tarragon, nutmeg, and allspice; used in flavors, fragrances, and some insect lures for fruit flies [1][3][4].

How You Are Exposed

Mainly by eating foods/herbs that contain it; also from using perfumes, essential oils, candles, and from workplace air in flavor/fragrance or pest-control settings [3][4].

Why It Matters

IARC classifies it as possibly carcinogenic to humans (Group 2B), and NTP lists it as reasonably anticipated to be a human carcinogen, based largely on liver tumors in rodents [1][2].

Who Is at Risk

Workers handling essential oils, flavors, fragrances, or lures; people who frequently use scented/essential-oil products; heavy consumers of certain herbs/spices; those with liver disease may be more vulnerable [2][3][4].

How to Lower Your Exposure

Choose fragrance-free products; limit use of essential oils high in methyleugenol (e.g., basil, tarragon) and avoid leave-on cosmetics with it; ventilate when using scented items; follow workplace ventilation/PPE guidance [3][4].

References

  1. [1]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 101: Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water. Methyleugenol (2013).
  2. [2]U.S. NTP, Report on Carcinogens, 15th Edition. Methyleugenol (2021).
  3. [3]WHO/FAO JECFA, Safety evaluation of certain food additives and contaminants: Methyleugenol (Flavouring agent), WHO Food Additives Series.
  4. [4]U.S. EPA, Methyleugenol Hazard Summary (Technology Transfer Network Air Toxics).

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