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CAS 556-61-6

Methyl isothiocyanate

Methyl isothiocyanate (MITC) is a toxic, sharp‑smelling pesticide used as a soil fumigant and also formed when other fumigants like metam sodium break down. Breathing it can irritate eyes and lungs and, at high levels, cause serious breathing problems [1][2].

Where It Comes From

A soil fumigant pesticide; also forms in the air and soil when metam sodium or dazomet are applied [1].

How You Are Exposed

Mostly by inhaling air near recently treated fields (during application, tarp venting, or off‑gassing); on‑the‑job handling; less often from indoor air or water after spills [1][2].

Why It Matters

Strong irritant causing burning eyes, sore throat, cough, wheeze, headache, and nausea; high doses can trigger asthma‑like attacks or lung injury. No conclusive evidence of cancer in humans [1][2].

Who Is at Risk

Farmworkers and applicators; residents close to fields; children, older adults, and people with asthma/COPD; anyone without proper protective gear [1][2].

How to Lower Your Exposure

Follow local fumigation notices and buffer zones; stay indoors with windows closed and HVAC on recirculate during nearby applications; avoid treated soil; workers must use label‑required PPE and monitoring [1][2].

References

  1. [1]U.S. EPA. Reregistration Eligibility Decision for Methyl Isothiocyanate (MITC). Office of Pesticide Programs, 2009.
  2. [2]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Methyl isothiocyanate. Updated ed. (accessed 2024).

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