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CAS 78-93-3

Methyl ethyl ketone

Potential EDCVOC

Methyl ethyl ketone (MEK), or 2-butanone, is a fast-evaporating solvent used in paints, coatings, and adhesives. It can irritate eyes, skin, and lungs; high levels can affect the nervous system [1][2].

Where It Comes From

Making/using paints, inks, coatings, adhesives, and degreasers; auto repair and furniture work. Also in tobacco smoke, vehicle exhaust, and some foods [1].

How You Are Exposed

Breathing vapors at work or during home projects (especially indoors); skin contact with liquid; sometimes from nearby industrial air or water [1][2].

Why It Matters

Short-term exposure can cause irritation, headache, and dizziness; very high levels may cause unconsciousness. It can dry/irritate skin and may make other solvents (e.g., n-hexane) more harmful. Not known to cause cancer; some developmental effects seen in animals at high doses [1][2][3].

Who Is at Risk

Workers in manufacturing, painting, printing, or auto repair; people using solvent products in poorly ventilated spaces; pregnant people and children; those with asthma [1][2].

How to Lower Your Exposure

Choose MEK-free products; use outdoors or with strong ventilation; keep containers closed; avoid open pans; wear gloves and eye protection; follow workplace controls and Safety Data Sheets [1][2].

References

  1. [1]ATSDR. ToxFAQs for 2-Butanone (MEK). Agency for Toxic Substances and Disease Registry. https://www.atsdr.cdc.gov/toxfaqs/tfacts29.pdf
  2. [2]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Methyl ethyl ketone. https://www.cdc.gov/niosh/npg/npgd0390.html
  3. [3]EPA IRIS. 2-Butanone (methyl ethyl ketone) Assessment Summary. U.S. Environmental Protection Agency. https://iris.epa.gov/chemical/0088

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