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CAS 109-77-3

Malononitrile

Malononitrile is a manufactured liquid used to make dyes, medicines, and other chemicals. It is highly toxic because it can release cyanide in the body or when heated/burned, which can quickly harm the brain and heart [1][2].

Where It Comes From

Made in chemical plants; used as an intermediate for pharmaceuticals, dyes, agrochemicals, and resins; found in research labs [2].

How You Are Exposed

Breathing vapors or mists where it’s made or used, skin/eye contact with liquid, or being near a spill or fire that can release hydrogen cyanide gas; contaminated water is possible after incidents [1][2].

Why It Matters

Short, high exposures can cause headache, dizziness, nausea, confusion, breathing trouble, seizures, cardiac arrest, and death; it can irritate eyes/skin [1][2][3].

Who Is at Risk

Workers in chemical manufacturing or labs; emergency responders to fires/spills; people with heart/lung disease, pregnant people, and children may be more vulnerable [1][3].

How to Lower Your Exposure

At work, use closed systems/ventilation and appropriate gloves, eye, and respiratory protection; follow spill/fire procedures. In the community, follow official guidance, avoid affected areas/water until cleared, and store/dispose chemicals properly [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Cyanide. U.S. CDC/ATSDR.
  2. [2]New Jersey Dept. of Health. Hazardous Substance Fact Sheet: Malononitrile (CAS 109-77-3).
  3. [3]WHO. Hydrogen cyanide and cyanides: Human health aspects (CICAD 61).

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