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CAS 121-75-5

Malathion

Potential EDCPesticidesCarcinogen

Malathion is a toxic organophosphate insecticide used on crops and for mosquito control. It matters because it can harm the nervous system and has been linked to cancer risk [1][2].

Where It Comes From

Widely used in agriculture, home gardens, and public health spraying; it can convert to malaoxon, a more toxic breakdown product, and be found in air, soil, dust, and water near applications [1][3].

How You Are Exposed

Eating residues on fruits and vegetables; breathing spray or drift during/after outdoor applications; skin contact when using or entering treated areas; drinking contaminated water near treated sites [1][3].

Why It Matters

Malathion inhibits acetylcholinesterase, causing headaches, nausea, sweating, weakness, and breathing problems; severe poisoning can be life‑threatening. IARC classifies malathion as probably carcinogenic to humans (Group 2A) [1][2].

Who Is at Risk

Farmers and pesticide applicators; people living near fields or spray routes; infants and children; pregnant people; pets and aquatic life are especially sensitive [1][2][3].

How to Lower Your Exposure

Follow local spray advisories; stay indoors and close windows during spraying and until residues dry; bring toys/pets inside; wash, peel, or cook produce; use only labeled products and wear gloves/eye protection; store/dispose pesticides safely; prevent runoff to water [1][3][4].

References

  1. [1]ATSDR. ToxFAQs for Malathion. https://www.atsdr.cdc.gov/toxfaqs/tfacts154.pdf
  2. [2]IARC Monographs, Volume 112: Malathion (2015). https://publications.iarc.fr/549
  3. [3]EPA. Malathion – Overview and risk information. https://www.epa.gov/ingredients-used-pesticide-products/malathion
  4. [4]CDC. Aerial spraying and mosquito control: Reducing exposure. https://www.cdc.gov/mosquitoes/mosquito-control/community/aerial-spraying.html

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