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CAS 29457-72-5

Lithium (perfluorooctane)sulfonate

Lithium (perfluorooctane)sulfonate is a salt of PFOS, a man‑made “forever chemical” used as a powerful surfactant in industry. It persists in the environment, can build up in people, and is linked to health harms [1][2].

Where It Comes From

Metal plating mist suppressants, firefighting foams (AFFF), stain/water‑repellent treatments; PFOS-related substances can break down to PFOS in the environment [1][2].

How You Are Exposed

Drinking contaminated water, eating contaminated fish/food, indoor dust, some products, and certain jobs (plating, firefighting, fluorochemical manufacturing) [1][3].

Why It Matters

Associated with decreased vaccine response, higher cholesterol, liver and thyroid changes, and developmental effects; PFOS and its salts are possibly carcinogenic (IARC Group 2B). EPA set a very low drinking‑water limit for PFOS [1][2][4][5].

Who Is at Risk

Workers handling PFAS or AFFF; people in communities near airports, military sites, plating facilities, or contaminated water; pregnant people, infants, and children; those eating local fish from affected waters [1][2][3].

How to Lower Your Exposure

Check local water quality; use home filters certified to reduce PFAS (NSF/ANSI 53 or 58); follow fish advisories; wet‑dust and use a HEPA vacuum; choose PFAS‑free products; follow workplace protections [2][3][1].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (including PFOS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. National Primary Drinking Water Regulation for PFAS (Final Rule). 2024. https://www.epa.gov/sdwa-and-pfas
  3. [3]CDC/ATSDR. PFAS and Your Health – Exposure and Health Effects. https://www.atsdr.cdc.gov/pfas
  4. [4]NTP. Monograph on Immunotoxicity Associated with PFOA and PFOS. 2016/2020 update. https://ntp.niehs.nih.gov
  5. [5]IARC. Press Release No. 264: PFOA (Group 1) and PFOS (Group 2B). 2023. https://www.iarc.who.int/news-events/iarc-monographs-evaluate-pfoa-and-pfos/

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