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CAS 25311-71-1

Isofenphos

Isofenphos is a toxic organophosphate insecticide once used mainly on turf (lawns, golf courses) and some crops. It matters because it harms the nervous system by blocking cholinesterase, which can cause poisoning at high exposures [1][2].

Where It Comes From

Past pesticide applications; in the U.S., all product registrations were canceled in 1999, though it may still be used elsewhere [1].

How You Are Exposed

Skin contact or inhalation during mixing or applying; contact with recently treated soil or turf; accidental swallowing of contaminated dust, soil, or water [2][3].

Why It Matters

Can cause headache, dizziness, sweating, nausea, vomiting, pinpoint pupils, and weakness; severe cases can lead to breathing problems, seizures, or death. Repeated exposures may cause longer-lasting nerve and mood/attention effects [2][3].

Who Is at Risk

Pesticide applicators and groundskeepers; people near treated areas; children and pets playing on recently treated turf [2][3].

How to Lower Your Exposure

In the U.S., avoid old/illegal stocks; follow product labels and re-entry intervals; keep kids and pets off treated areas until allowed; use protective gear when handling pesticides; wash hands/clothes after possible contact; seek medical care promptly if symptoms occur [1][2][3].

References

  1. [1]U.S. EPA. Isofenphos; Product Cancellation Order. Federal Register 64 FR 36722–36727 (July 7, 1999).
  2. [2]U.S. EPA. Recognition and Management of Pesticide Poisonings, 7th ed. Organophosphate insecticides (2023).
  3. [3]ATSDR. Case Studies in Environmental Medicine: Cholinesterase Inhibitors (2013, updated).

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