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CAS 193-39-5

Indeno[1,2,3-c,d]Pyrene

CarcinogenVOC

Indeno[1,2,3-c,d]pyrene (IcdP) is a polycyclic aromatic hydrocarbon formed when fuel, wood, or other materials burn incompletely. Found in soot and exhaust, it raises cancer and air‑quality concerns [1][2][3].

Where It Comes From

traffic and diesel exhaust; wood/coal stoves; wildfires; tobacco smoke; some industries; it sticks to fine air particles [1][4].

How You Are Exposed

breathing polluted or smoky air; eating charred/grilled or smoked foods; contact with road dust/soil; certain jobs (asphalt, foundry, firefighting, vehicle repair) [1][4].

Why It Matters

can damage DNA; EPA classifies it as a probable human carcinogen; IARC deems it possibly carcinogenic (Group 2B). PAH mixtures are linked to breathing and developmental effects [2][3][1][4].

Who Is at Risk

people near heavy traffic or industry; users of wood stoves; workers around combustion byproducts; smokers and those exposed to secondhand smoke; infants, children, and pregnant people [1][4].

How to Lower Your Exposure

avoid tobacco smoke; use and maintain vented, clean‑burning heaters; limit charred/smoked foods; reduce time near heavy traffic; check air quality and use filtration on smoky days; wet‑wipe dust; wash hands after outdoor activities [1][4].

References

  1. [1]ATSDR. Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs). Agency for Toxic Substances and Disease Registry.
  2. [2]U.S. EPA. IRIS: Indeno(1,2,3-cd)pyrene (CASRN 193-39-5).
  3. [3]IARC. Monographs Vol. 92: Some Non-heterocyclic Polycyclic Aromatic Hydrocarbons; classification of Indeno(1,2,3-cd)pyrene (Group 2B).
  4. [4]WHO. Air Quality Guidelines (chapter on Polycyclic Aromatic Hydrocarbons).

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