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CAS 28655-71-2

Heptachlorobiphenyl

Heptachlorobiphenyl is a specific polychlorinated biphenyl (PCB) congener—part of a group of man‑made oils once used in electrical equipment and some building materials. PCBs persist for decades, build up in fat, and can harm health [1][2][3].

Where It Comes From

Legacy PCB mixtures (Aroclors) in old transformers/capacitors, caulk/paint (pre-1979), contaminated soils/sediments, and waste sites; it accumulates in fish and wildlife [1][2][3].

How You Are Exposed

Eating contaminated fish/seafood, meat, or dairy; breathing indoor air/dust in older buildings; contact during electrical work or renovation; transfer during pregnancy and breastfeeding [1][2][4].

Why It Matters

PCBs cause cancer in humans and can affect the immune system, thyroid and liver, and children’s brain development, especially with prenatal/early-life exposure [1][3][5][6].

Who Is at Risk

People who frequently eat contaminated sport-caught fish, workers handling old electrical gear or doing demolition/renovation, residents near PCB sites, pregnant people, infants, and young children [1][2][3].

How to Lower Your Exposure

Follow local fish advisories; trim fat/skin and cook so fat drips away; reduce dust (HEPA vacuum, wet-wipe); avoid sanding old caulk; use protective gear and hygiene at work; seek professional PCB abatement [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Polychlorinated Biphenyls (PCBs). https://www.atsdr.cdc.gov/toxprofiles/tp17.pdf
  2. [2]U.S. EPA. Learn about Polychlorinated Biphenyls (PCBs). https://www.epa.gov/pcbs/learn-about-polychlorinated-biphenyls-pcbs
  3. [3]WHO. Polychlorinated biphenyls (PCBs) fact sheet. https://www.who.int/news-room/fact-sheets/detail/pcbs
  4. [4]CDC. Biomonitoring Summary: Polychlorinated Biphenyls (PCBs). https://www.cdc.gov/biomonitoring/PCBs_BiomonitoringSummary.html
  5. [5]IARC Monographs Vol. 107: Polychlorinated Biphenyls and Polybrominated Biphenyls. https://publications.iarc.fr/Book-And-Report-Series/Iarc-Monographs/Polychlorinated-Biphenyls-And-Polybrominated-Biphenyls-2016
  6. [6]NTP. Report on Carcinogens: Polychlorinated Biphenyls (PCBs). https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/roc

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