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CAS 171

Glycol Ethers

VOCHAP

Glycol ethers are a family of solvents used in water-based paints, cleaners, brake fluids, and electronics manufacturing. Some types can irritate eyes and lungs, harm red blood cells, and affect fertility and fetal development [1][2][3].

Where It Comes From

Consumer products (paints/varnishes, glass and degreasing cleaners, inks, brake fluid) and workplace processes; vapors can linger indoors after use [1][2].

How You Are Exposed

Breathing vapors during use, skin contact with liquids or wet surfaces, and contaminated work clothes; highest exposures occur at work [1][2].

Why It Matters

Short-term effects include irritation, headaches, nausea. High or repeated exposure can damage red blood cells (e.g., 2‑butoxyethanol) and affect liver/kidneys; certain ethylene glycol ethers (2‑methoxyethanol, 2‑ethoxyethanol) are linked to reduced fertility and developmental effects in humans and animals [1][2][3].

Who Is at Risk

Painters, custodial/cleaning staff, printing/auto repair and semiconductor workers; pregnant workers and fetuses; people using these products in small, poorly ventilated rooms [1][3].

How to Lower Your Exposure

Choose products without 2‑methoxyethanol/2‑ethoxyethanol (or their acetates); use outdoors or with strong ventilation; wear solvent‑resistant gloves and avoid skin contact; keep containers closed; wash after use; employers should substitute safer products and provide protective equipment [1][2][3].

References

  1. [1]ATSDR. ToxFAQs for 2-Butoxyethanol and 2-Butoxyethanol Acetate.
  2. [2]ATSDR. Toxicological Profile for 2-Methoxyethanol, 2-Ethoxyethanol, and their Acetates.
  3. [3]NTP-CERHR. Monograph on the Potential Human Reproductive and Developmental Effects of Ethylene Glycol Ethers (2-ME, 2-EE, and their acetates).

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