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CAS 151-56-4

Ethyleneimine (Aziridine)

CarcinogenMutagen

Ethyleneimine (aziridine) is a highly reactive, flammable industrial chemical used to make resins, coatings, and other products. It is very irritating and corrosive, and long-term exposure may increase cancer risk [1][2][3].

Where It Comes From

Made and used as a monomer and crosslinker for polyethylenimine, paper and textile treatments, adhesives, and ion‑exchange resins; releases can occur during production, use, storage, and spills [3][4].

How You Are Exposed

Mainly by breathing vapors at work or through skin/eye contact; the public may be exposed near facilities or during transport accidents [3][4].

Why It Matters

Causes severe eye, skin, and respiratory burns; headache, nausea, and lung injury can occur. It is mutagenic and classified as possibly carcinogenic (IARC 2B) and reasonably anticipated to be a human carcinogen (NTP) [1][2][4].

Who Is at Risk

Workers who make or use it; lab staff; maintenance and emergency responders; people with asthma or skin conditions may be more sensitive to irritation [3][4].

How to Lower Your Exposure

Use closed systems and local exhaust; wear chemical‑resistant gloves, goggles/face shield, and appropriate respiratory protection; follow spill plans. Communities should follow incident alerts and stay upwind/indoors during releases; seek medical care after significant exposure [3][4].

References

  1. [1]IARC Monographs: Aziridine (Ethyleneimine), Group 2B. International Agency for Research on Cancer.
  2. [2]NTP Report on Carcinogens: Aziridine (Ethyleneimine) — Reasonably Anticipated to be a Human Carcinogen. National Toxicology Program.
  3. [3]CDC/NIOSH Pocket Guide to Chemical Hazards: Aziridine. Centers for Disease Control and Prevention.
  4. [4]WHO/ILO IPCS International Chemical Safety Card (ICSC 0284): Aziridine. World Health Organization.

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