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CAS 110-49-6

Ethylene Glycol Monomethyl Ether Acetate

Developmental_ToxicityMale_Repro_Toxicity

Ethylene glycol monomethyl ether acetate (EGMEA), also called 2-methoxyethyl acetate, is a powerful solvent used in paints, inks, and electronics manufacturing. It is toxic—especially to fertility and fetal development—and can also affect the blood [1][2][3].

Where It Comes From

Industrial coatings, paints, lacquers, printing inks, cleaning agents, and semiconductor/photoresist processes [2][3].

How You Are Exposed

Breathing vapors during use, skin contact with liquid, working in areas with poor ventilation, or living near facilities that use it [1][2].

Why It Matters

Short-term exposure can irritate eyes and airways and cause headache or nausea; repeated or high exposures are linked to reduced fertility, miscarriage/birth defects, and anemia [1][2][3].

Who Is at Risk

Workers in painting, printing, electronics/semiconductor manufacturing, and labs; people who are pregnant or trying to conceive; anyone with frequent skin contact or inadequate ventilation [1][2].

How to Lower Your Exposure

Choose products labeled glycol-ether–free; check labels/SDS for “2‑methoxyethanol,” “2‑methoxyethyl acetate,” “EGMEA,” or “Cellosolve acetate”; ventilate well; avoid skin contact; wear chemical-resistant gloves (e.g., butyl rubber) and eye protection; at work, use substitution, closed systems, local exhaust, and PPE per NIOSH/OSHA guidance [1][2][3][4].

References

  1. [1]CDC/NIOSH. Pocket Guide to Chemical Hazards: 2-Methoxyethyl acetate (CAS 110-49-6).
  2. [2]ATSDR. Toxicological Profile for 2-Methoxyethanol and 2-Methoxyethyl Acetate.
  3. [3]WHO/IPCS. CICAD 15: 2-Methoxyethanol, 2-Ethoxyethanol, and their acetates.
  4. [4]U.S. EPA. Hazard Summary for Glycol Ethers.

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