Where It Comes From
Made for use as an organic solvent and process chemical; releases can occur during industrial use, storage, and lab handling [1][2][3].
How You Are Exposed
Breathing vapors at work, skin or eye contact with liquid, or from spills; consumer exposure is uncommon [1][2].
Why It Matters
Short-term exposure can cause irritation, headache, and drowsiness; very high levels may depress the central nervous system. It’s highly flammable and a peroxide former, posing fire/explosion hazards. As a volatile organic compound (VOC), emissions can contribute to smog/ground-level ozone [1][2][4].
Who Is at Risk
Workers who handle solvents (lab staff, chemical manufacturing, coatings) and people in poorly ventilated spaces; those with asthma or lung disease may be more sensitive to irritation [1][4].
How to Lower Your Exposure
Use in a fume hood or well-ventilated area; avoid skin contact (wear gloves and eye protection); keep containers closed, away from heat/ignition; date/test/discard old stock to prevent peroxide buildup; follow your Safety Data Sheet; report spills/odors and increase ventilation [1][2][4].
References
- [1]NOAA/EPA. CAMEO Chemicals: Ethylene glycol diethyl ether (CAS 629-14-1). https://cameochemicals.noaa.gov
- [2]NIH/NLM. PubChem Compound Summary: 1,2-Diethoxyethane (CAS 629-14-1). https://pubchem.ncbi.nlm.nih.gov/compound/1_2-Diethoxyethane
- [3]U.S. EPA. CompTox Chemicals Dashboard: 629-14-1. https://comptox.epa.gov/dashboard/chemical/details/629-14-1
- [4]U.S. EPA. Volatile Organic Compounds (VOCs) and indoor air. https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impact-indoor-air-quality