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CAS 541-41-3

Ethyl chloroformate

PesticidesCorrosive

Ethyl chloroformate is a colorless, pungent liquid used to make medicines, pesticides, and other chemicals. It is highly toxic and corrosive, especially to the eyes and lungs, and reacts strongly with moisture to release irritating gases [1][2].

Where It Comes From

Made and used in chemical manufacturing and research labs as a reactive intermediate/reagent [1][2].

How You Are Exposed

Mainly by breathing vapors at work or during spills; it can also burn skin and eyes on contact. General public exposure is rare and usually linked to accidents near facilities or during transport [1][2][3].

Why It Matters

Can cause severe eye and skin burns, intense throat and lung irritation, and dangerous delayed lung injury (pulmonary edema) after inhalation. Fumes from reactions can be highly irritating (e.g., hydrogen chloride) [1][2].

Who Is at Risk

Chemical and pharma workers, lab staff, transport and waste handlers, and emergency responders; people with asthma or lung disease may be more sensitive [1][2].

How to Lower Your Exposure

At work, use closed systems, local exhaust, and proper PPE; have spill/first-aid plans. In a community incident, stay upwind, avoid fumes, follow local alerts, and shelter in place or evacuate as directed [1][2][3].

References

  1. [1]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Ethyl chloroformate.
  2. [2]EPA/NOAA. CAMEO Chemicals: Ethyl chloroformate.
  3. [3]NIH/NLM. PubChem Compound Summary: Ethyl chloroformate.

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