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CAS 53-16-7

ESTRONE

Organic Chemicals, except for PFASPotential EDCCarcinogen

Estrone (E1) is a natural estrogen hormone found in people and animals and used in some hormone medicines. It can enter the environment and, like other steroidal estrogens, is linked to cancer with long-term exposure [1][2].

Where It Comes From

Excreted by people and livestock; wastewater effluent and biosolids; runoff from manure‑amended fields; discharges from pharmaceutical manufacturing [3][5].

How You Are Exposed

Drinking or swimming in water affected by sewage or farm runoff; eating fish from impacted waters; medical use of estrogen therapy [1][3].

Why It Matters

Steroidal estrogens (including estrone) are known human carcinogens and can disrupt reproductive and developmental systems; very low levels harm aquatic life [1][2][3].

Who Is at Risk

People using estrogen medications; pregnant people, infants, and adolescents (developing hormonal systems); communities near wastewater discharges or large animal operations that rely on local surface or groundwater [1][2][3][5].

How to Lower Your Exposure

Do not flush medications; use take‑back programs; consider certified activated carbon or reverse‑osmosis filters to reduce estrogens in drinking water; follow local fish advisories [3][4].

References

  1. [1]NTP. Report on Carcinogens, 15th Ed. Estrogens, Steroidal. U.S. DHHS.
  2. [2]WHO/UNEP. State of the Science of Endocrine Disrupting Chemicals 2012.
  3. [3]WHO. Pharmaceuticals in Drinking-water. 2011.
  4. [4]U.S. EPA. Collecting and Disposing of Unwanted Medicines.
  5. [5]U.S. EPA. Pharmaceuticals and Personal Care Products (PPCPs) in Water.

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