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CAS 136-45-8

Dipropyl isocinchomeronate

PesticidesCarcinogen

Dipropyl isocinchomeronate (also called MGK Repellent 326) is a synthetic insect repellent used in some consumer, outdoor, and pet products. EPA reviews find low acute toxicity when used as directed, though it can irritate skin or eyes at higher exposures [1][2].

Where It Comes From

Synthetic repellent active used in some sprays, treated gear, outdoor area products, and flea/tick pet collars [1][2].

How You Are Exposed

Skin contact when applying, breathing mists indoors/outdoors, touching treated pets or gear, and workplace handling [1][2].

Why It Matters

Can cause mild skin/eye irritation; overall acute toxicity is low in studies. Human long‑term data are limited, and there are no major cancer classifications [1][2].

Who Is at Risk

Workers and frequent users; young children who touch treated items and mouth hands; people with sensitive skin [1][3].

How to Lower Your Exposure

Use EPA‑registered products as directed; apply with ventilation; avoid eyes and broken skin; wash hands/skin after use; for pet collars, fit and handle per label and keep infants from chewing/handling; store out of reach [1][3].

References

  1. [1]U.S. Environmental Protection Agency (EPA). Pesticide registration review materials for Dipropyl isocinchomeronate (MGK Repellent 326, PC Code 077501). Office of Pesticide Programs.
  2. [2]U.S. EPA CompTox Chemicals Dashboard. Dipropyl isocinchomeronate (CASRN 136-45-8).
  3. [3]Centers for Disease Control and Prevention (CDC). Guidance on using insect repellents safely.

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