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CAS 111-77-3

Diethylene Glycol Monomethyl Ether

Diethylene glycol monomethyl ether (DEGME) is a glycol ether solvent used in paints, inks, cleaners, and some brake fluids. It can be absorbed through the skin and by breathing vapors; repeated exposure can affect fertility and harm the developing fetus [1][2].

Where It Comes From

Made and used as a solvent in water‑based paints/coatings, printing inks, cleaning formulations, dyes, and automotive brake fluids [1][3].

How You Are Exposed

Breathing vapors or mists at work; skin contact with wet products; short‑term indoor air during painting/cleaning; accidental spills [1][3].

Why It Matters

Can irritate eyes and skin; high levels may cause headache and dizziness. Animal and worker data show reproductive and developmental effects; EPA health benchmarks are based on these findings [1][2].

Who Is at Risk

Workers who handle paints, inks, cleaners, or brake fluids; people who are pregnant or trying to conceive; anyone with frequent skin contact at work [1][2].

How to Lower Your Exposure

Use products with fewer or no glycol ethers; ventilate well; keep containers closed; avoid skin contact—use chemical‑resistant gloves and eye protection; wash promptly; follow workplace exposure controls and monitoring [1][2][3].

References

  1. [1]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: 2-(2-Methoxyethoxy)ethanol (CAS 111-77-3).
  2. [2]U.S. EPA. Integrated Risk Information System (IRIS): 2-(2-Methoxyethoxy)ethanol (CASRN 111-77-3).
  3. [3]U.S. EPA. Hazard Summary: Glycol Ethers (TTN Air Toxics).

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