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CAS 18912-80-6

Diethylene Glycol Monoisobutyl Ether

Diethylene glycol monoisobutyl ether (DEGMBE) is a glycol-ether solvent used in water-based paints, cleaners, inks, and coatings. It can irritate eyes and skin and, at higher levels, affect the nervous system; some related glycol ethers have shown reproductive effects, so limiting exposure is prudent [1][2].

Where It Comes From

Used as a solvent/coalescent in latex paints, cleaners, printing inks, and metalworking fluids; released to air during product use and some industrial processes [1][3].

How You Are Exposed

Breathing vapors while painting or cleaning, skin contact from spills or sprays, and workplace air where products are mixed or applied; less often from indoor dust or nearby facility emissions [1][2].

Why It Matters

Short-term exposure may cause eye/skin irritation, headache, dizziness, and nausea; very high doses in studies affected liver/kidneys. EPA lists glycol ethers as hazardous air pollutants, reflecting potential health concerns [1][3].

Who Is at Risk

Workers in painting, printing, cleaning, coating, or metalworking; pregnant workers; infants/children; people with asthma or skin conditions; anyone in poorly ventilated spaces [1][2].

How to Lower Your Exposure

Choose products with no/low glycol ethers or EPA Safer Choice-certified; ventilate well; wear nitrile gloves and avoid spraying; keep containers closed; follow workplace controls and use local exhaust [2][4].

References

  1. [1]ATSDR. Toxicological Profile for Glycol Ethers. Agency for Toxic Substances and Disease Registry.
  2. [2]CDC/NIOSH. Glycol Ethers — Workplace Safety & Health Topics.
  3. [3]U.S. EPA. Hazardous Air Pollutants (CAA 112): Glycol Ethers category.
  4. [4]U.S. EPA. Safer Choice Program — About and Criteria.

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