Where It Comes From
Manufacturing or servicing of refrigeration/air-conditioning chillers, foam blowing, and precision cleaning solvents; some fire-suppression blends also contain it [1][2].
How You Are Exposed
Breathing vapors from leaks or use at work; indoor air near equipment; skin contact with the cold liquid; accidental releases during maintenance [1][3].
Why It Matters
Short-term exposure can cause dizziness, headache, drowsiness, and eye/skin irritation; very high levels may trigger irregular heartbeat or unconsciousness; repeated high exposure has been linked to liver effects. It also depletes ozone and is being phased down [1][2][3].
Who Is at Risk
Refrigeration technicians; solvent cleaning and foam workers; people in small, poorly ventilated spaces with leaking equipment; individuals with heart or liver disease [1][3].
How to Lower Your Exposure
Ensure good ventilation; fix leaks promptly; follow EPA refrigerant recovery rules; use proper PPE and avoid enclosed spaces; never heat or burn it; consider safer alternatives approved by EPA [2][3].
References
- [1]WHO IPCS. CICAD 26: 2,2-Dichloro-1,1,1-trifluoroethane (HCFC-123). 2000.
- [2]U.S. EPA. Ozone Layer Protection: Class II Ozone-Depleting Substances (HCFCs) and Phaseout.
- [3]CDC/NIOSH. Pocket Guide to Chemical Hazards: 2,2-Dichloro-1,1,1-trifluoroethane (HCFC-123).