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CAS 79-43-6

DICHLOROACETIC ACID

Disinfection ByproductsPotential EDCCarcinogenDevelopmental_ToxicityMale_Repro_ToxicityCorrosive

Dichloroacetic acid (DCA) is a toxic disinfection byproduct that can form when chlorine is used to treat drinking water. It can affect the liver and nervous system and is regulated in U.S. drinking water as part of the haloacetic acids group (HAA5) [1][3][4].

Where It Comes From

Forms during chlorination of water with natural organic matter; also occurs in chlorinated swimming pools and some industrial processes [1][2].

How You Are Exposed

Mainly by drinking tap water; smaller amounts from inhalation/skin contact during bathing or swimming; very limited workplace exposure in specialized labs/industry [1][2].

Why It Matters

Can cause liver and nerve effects; long-term high exposures caused cancers in laboratory animals; human cancer evidence is limited/uncertain. Regulated as part of HAA5 (sum limit 60 µg/L in U.S. public water) [1][2][3].

Who Is at Risk

People who drink a lot of tap water where HAA levels are high; infants (especially formula prepared with tap water), pregnant people, and those with liver disease [1][2].

How to Lower Your Exposure

Check your water utility’s Consumer Confidence Report; use a home filter certified to reduce haloacetic acids (activated carbon or reverse osmosis); use cold water for drinking/cooking; avoid swallowing pool water and improve pool ventilation [2][3].

References

  1. [1]ATSDR. Toxicological Profile for Dichloroacetic Acid (DCA). Agency for Toxic Substances and Disease Registry.
  2. [2]WHO. Dichloroacetic Acid in Drinking-water: Background document for development of WHO Guidelines for Drinking-water Quality. World Health Organization.
  3. [3]EPA. National Primary Drinking Water Regulations: Haloacetic Acids (HAA5/HAA9) and Stage 2 Disinfectants/Disinfection Byproducts Rule. U.S. Environmental Protection Agency.
  4. [4]EPA IRIS. Dichloroacetic acid (CASRN 79-43-6). Integrated Risk Information System, U.S. Environmental Protection Agency.

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