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CAS 90454-18-5

Dichloro-1,1,2-trifluoroethane

Dichloro-1,1,2-trifluoroethane is a man-made hydrochlorofluorocarbon (HCFC) used in some refrigerants and industrial cleaners. Like related HCFCs, it can be harmful at high levels and it damages the ozone layer [1][2][3].

Where It Comes From

Manufacturing and use of HCFC refrigerants and foam‑blowing agents, and some solvent cleaning processes; leaks from older equipment; improper disposal [1].

How You Are Exposed

Breathing vapors near equipment leaks or at work; less often through skin or eye contact. Vapors can build up in poorly ventilated areas [2][3].

Why It Matters

Short‑term exposure can cause headache, dizziness, and drowsiness; very high levels may lead to irregular heartbeat or unconsciousness. Repeated workplace exposure to a closely related HCFC (HCFC‑123) has affected the liver. HCFCs also deplete the ozone layer and contribute to climate change [1][2][3].

Who Is at Risk

Refrigeration/AC technicians, foam and solvent workers, and people near leaks in small or poorly ventilated spaces [1][3].

How to Lower Your Exposure

Choose non‑HCFC products when possible; maintain and promptly repair equipment; ensure good ventilation; avoid confined‑space work during leaks; follow labels/SDS, use protective gear, and recover/dispose refrigerants per EPA rules [1].

References

  1. [1]U.S. EPA. Hydrochlorofluorocarbons (HCFCs): health and environmental information.
  2. [2]ATSDR. ToxFAQs: 2,2‑Dichloro‑1,1,1‑trifluoroethane (HCFC‑123).
  3. [3]ATSDR. ToxFAQs: Chlorodifluoromethane (HCFC‑22).

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