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CAS 21725-46-2

Cyanazine

Potential EDCPesticidesDevelopmental_ToxicityTeratogen

Cyanazine is a synthetic “triazine” herbicide once widely used on corn and other crops. It’s toxic and can reach drinking water from farm runoff or soil leaching, which is why exposure matters for health and the environment [1][3].

Where It Comes From

Agricultural use on row crops; residues and breakdown products can move from fields into streams and groundwater. Most U.S. uses were canceled by the early 2000s, but it can still be found where it was heavily applied or where use continues elsewhere [2][3].

How You Are Exposed

Drinking water from private wells or systems in farming regions; handling/applying pesticides; spray drift or contact with treated soil; residues on produce are generally low but possible [1][2][3].

Why It Matters

Triazines can affect the endocrine (hormone) system; animal studies show developmental and reproductive effects. EPA has classified cyanazine as a possible human carcinogen under earlier guidelines [1][2].

Who Is at Risk

Farmworkers and pesticide applicators; people using private wells near cropland; infants, children, and pregnant people; communities with older or minimally treated water sources [1][3].

How to Lower Your Exposure

Use certified activated‑carbon or reverse‑osmosis water filters; check your water utility’s report or test private wells for triazines; follow label directions and PPE if handling pesticides; avoid recently treated fields; wash and peel produce when appropriate [2][3].

References

  1. [1]U.S. EPA, Integrated Risk Information System (IRIS): Cyanazine (CASRN 21725‑46‑2).
  2. [2]U.S. EPA, Office of Pesticide Programs: Cyanazine regulatory documents (Fact Sheet/RED and cancellation notices).
  3. [3]U.S. EPA, 2018 Edition of the Drinking Water Standards and Health Advisories (cyanazine).

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