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CAS 1333-82-0

Chromium Trioxide

CarcinogenTeratogen

Chromium trioxide (also called chromic acid, a hexavalent chromium or Cr(VI) compound) is a highly toxic, corrosive oxidizer used in chrome plating and metal finishing. It matters because Cr(VI) causes cancer and can harm the lungs, skin, and other organs [1][2].

Where It Comes From

Chrome electroplating and anodizing; chromate primers/pigments and corrosion inhibitors; welding or cutting stainless steel; industrial air and water discharges [1][3].

How You Are Exposed

Breathing workplace fumes or dust; skin contact with solutions or contaminated dust; drinking water from affected wells or systems; living near plating/metal finishing facilities or waste sites [1][2].

Why It Matters

Linked to lung and sinonasal cancers; nose and lung irritation, asthma‑like symptoms, and nasal septum damage; skin ulcers (“chrome holes”) and allergic rashes; stomach, kidney, or liver effects after swallowing [1][2][3].

Who Is at Risk

Workers in electroplating, welding, and chromate coating/painting; nearby residents; people with asthma or skin conditions [1][3].

How to Lower Your Exposure

At work, use ventilation, enclosures, protective gear, and hygiene per safety rules; at home, test private wells if near industry, use certified treatment (e.g., reverse osmosis or anion exchange), avoid sanding chromate paints, and wash off residues promptly [1][3][4].

References

  1. [1]ATSDR. ToxFAQs for Chromium. Agency for Toxic Substances and Disease Registry. https://www.atsdr.cdc.gov/toxfaqs/tfacts7.html
  2. [2]IARC. Chromium(VI) compounds. IARC Monographs, Vol. 100C (2012). https://publications.iarc.fr/120
  3. [3]NTP. Chromium (hexavalent compounds). Report on Carcinogens, 15th Ed. https://ntp.niehs.nih.gov/whatwestudy/assessments/roc
  4. [4]EPA. Technical Fact Sheet – Hexavalent Chromium (2017). https://www.epa.gov/fedfac/technical-fact-sheet-chromium-vi-hexavalent-chromium

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