← All chemicals

CAS 75-72-9

Chlorotrifluoromethane (CFC-13)

Chlorotrifluoromethane (CFC-13) is a chlorofluorocarbon once used as a very low‑temperature refrigerant (R‑13). It can be harmful at high levels and is a long‑lived ozone‑depleting greenhouse gas, so production has been phased out in many countries [1][2].

Where It Comes From

Older refrigeration/freezer systems, industrial gas cylinders, and legacy stockpiles; new production is largely banned due to ozone depletion [2].

How You Are Exposed

Breathing leaked gas during equipment servicing, decommissioning, or accidental releases; skin/eye contact with the liquefied gas. The gas is heavier than air and can collect in low spaces [1][3].

Why It Matters

High concentrations can displace oxygen (simple asphyxiant), causing headache, dizziness, or unconsciousness; liquid contact can cause frostbite. When heated (e.g., in fires) it can break down into toxic gases. Environmentally, it depletes the ozone layer and contributes to climate change [1][2][3].

Who Is at Risk

Refrigeration technicians, workers handling cylinders or older systems, and anyone entering confined or poorly ventilated areas near a leak [1][2].

How to Lower Your Exposure

Use certified technicians and proper recovery equipment; never vent CFCs. Improve ventilation and use leak detection. Avoid confined spaces until air is tested; move away from low-lying areas during a release; upgrade to non‑ODS alternatives [1][2][3].

References

  1. [1]CDC/NIOSH Pocket Guide to Chemical Hazards: Chlorotrifluoromethane (R‑13).
  2. [2]U.S. EPA. Class I Ozone-Depleting Substances (CFCs) and phaseout under the Clean Air Act.
  3. [3]WHO/ILO IPCS. International Chemical Safety Card (ICSC): Chlorotrifluoromethane.

Track your exposure to Chlorotrifluoromethane (CFC-13)

Pollution Profile maps your lifetime exposure history to EPA-tracked chemicals.

Get early access

We use cookies and analytics to understand how people use Pollution Profile and improve the experience. We never sell your data. Learn more.