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CAS 10049-04-4

Chlorine dioxide

Chlorine dioxide is a yellow‑green gas used to disinfect drinking water and in some industries. It’s toxic: breathing high levels irritates the lungs, and swallowing concentrated solutions can cause serious illness [1][2].

Where It Comes From

Made on-site at water treatment plants and pulp/paper mills for disinfection and bleaching; breaks down to chlorite and chlorate [1][3].

How You Are Exposed

Workers may inhale it during water treatment, food sanitation, or pulp/paper bleaching; the public may encounter very low levels in tap water (within EPA limits) or from misuse of products [1][2][4].

Why It Matters

Short-term exposure causes cough, throat irritation, chest tightness; high levels can injure lungs. Swallowing strong solutions can cause vomiting, diarrhea, and red blood cell changes; children may be more sensitive [1][2][3].

Who Is at Risk

Workers; people with asthma or other lung disease; infants and young children [1][2][3].

How to Lower Your Exposure

At work, use ventilation, monitoring, and PPE; follow the NIOSH 0.1 ppm ceiling. Do not drink chlorine dioxide products; use water that meets EPA standards (MRDL 0.8 mg/L; chlorite MCL 1.0 mg/L) [2][1][4].

References

  1. [1]ATSDR. ToxFAQs for Chlorine Dioxide & Chlorite. Agency for Toxic Substances and Disease Registry.
  2. [2]CDC/NIOSH. Pocket Guide to Chemical Hazards: Chlorine dioxide (ClO2).
  3. [3]WHO. Guidelines for Drinking-water Quality (sections on chlorine dioxide, chlorite, and chlorate).
  4. [4]EPA. National Primary Drinking Water Regulations (MRDL for chlorine dioxide; MCL for chlorite).

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